Confirmation rates, sensitivity, specificity and significance of the applied molecular tests.

Table 2 shows the results of DRB PCR, cPCR, qPCR, cLAMP, and DRB LAMP from clinical samples of clinically suspected and confirmed BUD cases recruited at Agogo Presbyterian Hospital, Ghana, Tepa Government Hospital, Ghana, and at Centre Hospitalier Régional de Tsévié, Togo.N.A., not applicable.a Number of clinical samples tested.# indicates if the presented results refer to the number of samples–all other results refer to the number of patients or ¶the number of patients and samples was equal.b Results of the DRB PCR and cPCR were 100% concordant for all samples tested.c 95 percent confidence interval.d Specificity was calculated as proportion of truly positive test results out of all positive results of the same test, based on the results of qPCR as reference test.e Laboratory confirmation was defined as positive IS2404 qPCR test result of any sample tested per patient.* Significantly different proportions of positive results among all clinical samples tested by two different tests, calculated by McNemar test.Confirmation rates, sensitivity, specificity and significance of the applied molecular tests.