five

chimeric antibody

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NIAID Data Ecosystem2026-05-01 收录
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https://doi.org/10.7910/DVN/QMW69L
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The chimeric antibodies can be created by fusing murine variable domains, responsible for the binding activity, with human constant domains. These antibodies are 70% human and possess a fully human Fc portion, which makes them considerably less immunogenic in humans as well as allows them to interact with human effector cells and the complement cascade.
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2023-06-18
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