Tissue sensitivity to glucocorticoids is a key factor dictating outcome of their homeostatic and therapeutic action, whereby liver represents one of the major peripheral targets. Here, we used pigs ca
Supplementary Table S18. Half maximum inhibitory concentrations (IC50) for cisplatin, paclitaxel and olaparib in cell lines after CRISPR/Cas-9 mediated RB1 knockout.
BRCA1/2 mutations and homologous recombination deficiency (HRD) predispose to increased sensitivity to poly(ADP-ribose)polymerase (PARP) inhibitor treatment. Our aim was to evaluate the PARP inhibitor