A NeuroD1 AAV-Based Gene Therapy For Functional Brain Repair After Ischemic Injury Through In Vivo Astrocyte-To-Neuron Conversion
收藏NIAID Data Ecosystem2026-03-11 收录
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资源简介：
NeuroD1-mediated in situ astrocyte-to-neuron conversion can regenerate a large number of functional new neurons after ischemic injury. RNA-sequencing was conducted to confirm neuronal recovery after cell conversion at the mRNA level. Cortical tissues of healthy mice (n = 3), ischemic mice at 17 dpi with control or NeuroD1 virus (n = 2 for each) were collected. mRNA samples were extracted and sequenced.
创建时间：
2019-11-25
