We have attempted to validate in Aspergillus flavus the main in vitro methodologies that have been used to detect resistance in Aspergillus fumigatus. We developed a murine model with two A. flavus is
aCla, clarithromycin; Cli, clindamycin; Ery, erythromycin; Gm, gentamicin; Spc, spectinomycin; Str, streptomycin.bND, not done; DD503 is streptomycin resistant because of a chromosomal rpsL mutation.c