Heterogeneity in the expression of 35 proteins assessed by reverse-phase-protein-arrays.

There was considerable intratumoral heterogeneity in the expression of all 35 proteins analyzed, and even more pronounced variation amongst different patients.Intratumoral, differences between individual samples of the same primary tumor or between individual lymph node metastases from the same patient.CV, coefficient of variation given as percentage; Primary tumor, whole tumor including central, peripheral, and intermediate zone; LN, lymph node; Total, total case including all primary tumor and lymph node samples.Phospho, all phosphorylated proteins combined; Non-phospho, all non-phosphorylated proteins combined;Overall, all 35 proteins combined.