Targeting BRD4 Ameliorates Experimental Emphysema Via Suppressing both M1 and M2 alveolar macrophage polarization-1

BRD4 inhibition suppressed M2 macrophage polarization. Particularly, we deeply investigated the underlying molecular mechanism of how BRD4 regulate M2 genes expression. And finished this RNA-seq To investigate BRD4 inhibitors and degraders effect on the IL-4 induced M2 alveolar macrophage transcriptome, we finished the RNA-seq experiment.