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Suppression of Transcriptional Drift Extends C. elegans Lifespan by Postponing the Onset of Mortality

ChEBI2016-01-06 更新2026-07-12 收录

衰老分子机制

转录调控研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-63528 数据链接链接失效反馈

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资源简介：

Suppression of Transcriptional Drift Extends C. elegans Lifespan by Postponing the Onset of Mortality

应用场景：

创建时间：

2016-01-06

衰老分子机制

虫类基因调控

The molecular mechanisms of aging are unsolved fundamental biological questions. Caenorhabditis elegans is an ideal model organism for investigating aging. PUF-8, a PUF (Pumilio and FBF) protein in C.

中国科学院中国科学技术大学科学数据中心110

Summary of DAF-16::GFP Nuclear Localization Data.

衰老分子机制

胰岛素信号通路

Animals were scored for presence of nuclear puncta after treatment with DMSO, daf-2(RNAi), FLA or following a 2 hour heat-shock incubation at 37°C. A Student's T-Test was used to determine statistical

NIAID Data Ecosystem70

Impact of cognitive performance and normal aging on transcriptomic changes in the prefrontal cortex of rats. Impact of cognitive performance and normal aging on transcriptomic changes in the prefrontal cortex of rats

衰老分子机制

转录组学分析

We investigated how cognitive stimulation impacts gene expression in the prefrontal cortex (PFC), a brain region known to regulate higher cognitive functions including the control of attention, in you

NIAID Data Ecosystem60

Deep sequencing of small RNAs from whole nematode C. elegans during aging

衰老分子机制

MicroRNA调控

MicroRNAs (miRNAs) have been implicated in gene regulation in many complex processes, including aging. Moreover, expression levels of many miRNAs are altered during aging, though we know little about

NIAID Data Ecosystem70

Additional file 3 of SUMOylated non-canonical polycomb PRC1.6 complex as a prerequisite for recruitment of transcription factor RBPJ

引物序列资源

转录调控研究

Additional file 3: Table S2. Oligonucleotides and primers used for the study.

NIAID Data Ecosystem70