Crystal structure of TTK kinase domain in complex with compound 19
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/7clh
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of TTK kinase domain in complex with compound 19 Descriptor: 2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Dual specificity protein kinase TTK Authors: Kim, H.L, Cho, H.Y, Park, Y.W, Lee, Y.H, Son, J.B, Ko, E.H, Choi, H.G, Kim, N.D. Deposit date: 2020-07-21 Release date: 2021-05-12 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.9 Å) Cite: X-ray Crystal Structure-Guided Design and Optimization of 7 H -Pyrrolo[2,3- d ]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor. J.Med.Chem., 64, 2021
创建时间：
2020-07-21
