Respirasome open state 2 in presence of metformin (SC-MetO2)

Respirasome open state 2 in presence of metformin (SC-MetO2) Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, ... Authors: Teng, F, He, Z.X, Hu, Y.Q, Xu, C.Y, Guo, R.Y, Zhou, L. Deposit date: 2024-05-29 Release date: 2025-11-19 Last modified: 2026-02-04 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Hydrophilic metformin and hydrophobic biguanides inhibit mitochondrial complex I by distinct mechanisms. Nat.Struct.Mol.Biol., 33, 2026