Cu(OAc)2‑Mediated Cascade Annulation of Diarylalkyne Sulfonamides through Dual C–N Bond Formation: Synthesis of 5,10-Dihydroindolo[3,2‑b]indoles
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An unusual cascade reaction featuring annulation of diarylalkyne sulfonamides to form 5,10-dihydroindolo[3,2-b]indoles has been realized with Cu(OAc)2 as the sole oxidant. This unprecedented process encompasses two sequential C–N bond formations, allowing for an efficient synthesis of the biologically important indoloindole derivatives.
创建时间:
2016-07-11



