Nickel-Catalyzed Directed C6-Selective C–H Alkylation of 2‑Pyridones with Dienes and Activated Alkenes
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https://figshare.com/articles/dataset/Nickel-Catalyzed_Directed_C6-Selective_C_H_Alkylation_of_2_Pyridones_with_Dienes_and_Activated_Alkenes/4984598
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资源简介：
A pyridine-directed,
C6-selective nickel-catalyzed ring-contracting
C–H alkylation of 2-pyridones with 1,5-cyclooctadiene (cod)
has been developed. The reaction proceeds smoothly under external-ligand-free
conditions and is accelerated uniquely by a K3PO4 base. Preliminary mechanistic investigations with deuterium-labeled
substrates and related reactions with some alkenes are also disclosed.
创建时间：
2017-05-08
