Background: The role of microbes and their products in ankylosing spondylitis (AS) has been widely studied. We investigated alterations in the oral microbiota, immunity and metabolome in AS patients u
IntroductionAnkylosing spondylitis (AS) is a chronic inflammatory disorder with poorly defined pathogenic mechanisms. The integrated stress response (ISR), an evolutionarily conserved signaling networ
Ankylosing spondylitis (AS) is an immune-mediated inflammatory disorder that primarily affects the axial skeleton, especially the sacroiliac joints and spine. This results in chronic back pain and, in
Additional file 3: Table S3. Differentially expressed proteins (DEPs) in AS vs OA, AS vs gout, and AS vs RA comparison sets, defined as the proteins with > 1.5-fold-change and < 0.05 p-value. Gene sym
