SETDB1 promotes liver regeneration by elevating CSF3 expression in hepatocytes

NIAID Data Ecosystem2026-05-10 收录

肝脏再生机制

表观遗传调控

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP479333 数据链接链接失效反馈

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资源简介：

Raw data of in vivo CRISPR screen; RNA-seq and H3K9me3 CUT&Tag of mouse liver hepatocytes

创建时间：

2025-10-14

A prion accelerates proliferation at the expense of lifespan

朊病毒与细胞衰老

表观遗传调控

Organisms often commit to one of two strategies: living fast and dying young or living slow and dying old. In fluctuating environments, however, switching between these two strategies could be advanta

Alliance of Genome Resources00

DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]

表观遗传调控

甲基化反应机制

DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

NIAID Data Ecosystem00

An epigenetic switch in vascular phenotype augments anti-tumor immunity [bulkRNA-seq]

肿瘤免疫微环境

表观遗传调控

The abnormal tumor vasculature can present a barrier to the infiltration of anti-tumor immune cells, which impairs immune surveillance and response to immunotherapy. Here, we show that targeting the e

NIAID Data Ecosystem00

Effect of splenectomy on liver regeneration after 70% resection in a mouse model.

肝脏再生机制

脾切除与肝脏再生

In this work, the effect of splenectomy on liver regeneration was studied. For this purpose in the animals were reproduced splenectomy, and after 7 days 70% liver resection was performed. Animals in

NIAID Data Ecosystem00

Addressing the specific roles of histone modifications in transcriptional repression [RNA-seq]

组蛋白修饰转录抑制

表观遗传调控

Our understanding of epigenetic processes is based on the hypothesis that individual posttranslational modifications of DNA and histones, or combinations thereof, function to direct unique downstream

NIAID Data Ecosystem00

SETDB1 promotes liver regeneration by elevating CSF3 expression in hepatocytes

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