five

RARg bookmarking functions in prostate cancer (IMPACT-Seq)

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE254731
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To define the RARg complex in PCa cell models, including isogenic variants of 22Rv1, how this is targeted by miR-96, and regulates the AR cistrome, and how this is specifically enriched in G2/M cells and how these actions collectively shape the transcriptional programs associated with PCa outcomes. IMPACT-Seq was undertaken on HPr1AR or LNCaP cells transfected with 3' biotinylated miRIDIAN miR-96 mimic and scramble controls
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2024-02-29
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