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A novel chemical derivative(85) of THRB agonist

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Protein Data Bank Japan2024-11-20 更新2026-04-19 收录
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A novel chemical derivative(85) of THRB agonist Descriptor: 2-[[7-[4-(3,5-dimethylphenyl)carbonyl-2,6-dimethyl-phenoxy]-1-ethoxy-4-oxidanyl-isoquinolin-3-yl]carbonylamino]ethanoic acid, Isoform Beta-2 of Thyroid hormone receptor beta, Nuclear receptor coactivator 2 Authors: Yao, B.Q, Li, Y. Deposit date: 2022-01-15 Release date: 2022-05-18 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor beta Agonist. J.Med.Chem., 65, 2022

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2022-01-15
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