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DNA methylation and gene expression analyses in adipose tissue to identify new loci associated with T2D development in obesity

ChEBI2023-01-01 更新2026-07-12 收录

糖尿病表观遗传学

肥胖相关代谢疾病基因组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-11841 数据链接链接失效反馈

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DNA methylation and gene expression analyses in adipose tissue to identify new loci associated with T2D development in obesity

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创建时间：

2023-01-01

糖尿病表观遗传学

胰岛生物学

Diabetes-resistant and diabetes-prone female New Zealand Obese mice were classified based on liver fat content and early blood glucose concentrations at 10 weeks of age before the onset of T2D. By usi

NIAID Data Ecosystem80

Genome-wide histone modification profiling using ChIP-seq of diabetic or non-diabetic murine bone marrow derived macrophages (BMDM) and haematopoietic stem cells (HSC)

糖尿病表观遗传学

组蛋白修饰谱分析

Genome-wide histone modification profiling using ChIP-seq of diabetic or non-diabetic murine bone marrow derived macrophages (BMDM) and haematopoietic stem cells (HSC). Chromatin fragments were select

NIAID Data Ecosystem70

Differentially methylated genes.

DNA甲基化分析

糖尿病表观遗传学

The 20 CpG sites with the lowest P-values for the intra-pair methylation difference between type 2 diabetic and non-diabetic twins are shown for subcutaneous adipose tissue and skeletal muscle. The to

NIAID Data Ecosystem40

Long-Term Pancreatic Beta Cell Exposure to High Levels of Glucose but Not Palmitate Induces DNA Methylation within the Insulin Gene Promoter and Represses Transcriptional Activity

糖尿病表观遗传学

胰岛素基因调控

Recent studies have implicated epigenetics in the pathophysiology of diabetes. Furthermore, DNA methylation, which irreversibly deactivates gene transcription, of the insulin promoter, particularly th

Figshare2016-01-15 更新70

Homo sapiens Epigenomics

糖尿病表观遗传学

听力损失分子机制

Diabetes-related hearing loss (DRHL) is a complication of diabetes mellitus which is drawing more attention currently. DNA methylation plays a critical role in the pathogenesis of type 2 diabetes mell

NIAID Data Ecosystem60

DNA methylation and gene expression analyses in adipose tissue to identify new loci associated with T2D development in obesity

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