NEW EMBO MEMBER’S REVIEW
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NEW EMBO MEMBER’S REVIEW
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2001-07-16
相关数据集
Four new subunits of the Dam1–Duo1 complex reveal novel functions in sister kinetochore biorientation
We show here that Ask1p, Dad2p, Spc19p and Spc34p are subunits of the budding yeast Duo1p–Dam1p– Dad1p complex, which associate with kinetochores and localize along metaphase and anaphase spindles. An
PubMed Central2002-01-15 更新40
DNA polymerase β is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts
The repair of oxidative base lesions in DNA is a coordinated chain of reactions that includes removal of the damaged base, incision of the phosphodiester backbone at the abasic sugar residue, incorpor
PubMed Central2001-12-03 更新10
CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation
We characterized a new signaling pathway leading to the activation of cAMP-responsive element-binding protein (CREB) in several cell lines affected by mitochondrial dysfunction. In vitro kinase assays
PubMed Central2002-01-15 更新10
Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC
Ubiquitin-mediated proteolysis has emerged as a key mechanism of regulation in eukaryotic cells. During cell division, a multi-subunit ubiquitin ligase termed the anaphase promoting complex (APC) targ
PubMed Central2001-09-17 更新30
Ca(2+) sensor S100β-modulated sites of membrane guanylate cyclase in thephotoreceptor-bipolar synapse
This study documents the identity of a calcium- regulated membrane guanylate cyclase transduction system in the photoreceptor-bipolar synaptic region. The guanylate cyclase is the previously character
PubMed Central2002-06-03 更新10
