Expression data from in vitro healthy cells and malignant pleural mesothelioma cell lines infected by oncolytic attenuated measles virus or treated by exogenous type I interferon

We used microarrays to analyse antiviral response by mesothelioma cells sensitive or resistant to the oncolytic activity of measles virus 4 healthy cells and 12 malignant pleural mesothelioma cell lines were infected with measles virus (MV, MOI 1) or not infected (NI = basal expression) or were treated with type I interferon (IFN : IFN-alpha2 + IFN-Beta, 1000UI/mL) during 48 hours. Cells were lysed and RNA was extracted of each sample. This experiment was performed 3 times. RNA was quantified after purification and same quantity of RNA of the 3 experiments was pooled in the same tube for each sample. Then, RNA was analyzed with microarrays.