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Iridium-Catalyzed Annulation of <i>N</i>-Arylcarbamoyl Chlorides with Internal Alkynes

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NIAID Data Ecosystem2026-03-06 收录
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An iridium complex successfully catalyzed the annulation of various N-arylcarbamoyl chlorides with internal alkynes to afford 2-quinolones in good to excellent yields. The present reaction is widely applicable to substrates with various functionalities. An amide−iridacycle complex was isolated, and it is likely that such an iridacycle species is a key intermediate in the catalytic reaction.

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2016-02-24
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