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Temporal transcriptomic analysis of Tfh cells in lupus

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NIAID Data Ecosystem2026-03-12 收录
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Spleens were harvested from B6.Sle1.Yaa at 2, 4, and 7 months of age or from LCMV infected mice 8 days post infection. RNA-seq was employed to assess transcriptional changes in these cells throughout disease progression. Overall design: Sorted Tfh cells (CD4+CD44+GITR-PSGL-1loCXCR5hiPD-1hi) from 2, 4- and 7-month-old mice compared to naive CD4 T cells from B6.Sle1.Yaa mice

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2021-03-03
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