Staphylococcus aureus evades macrophage killing through NLRP3 dependent effects on mitochondrial trafficking. Mus musculus

Respiratory innate immunity requires alveolar macrophages, which are specifically targeted by the S. aureus toxin alpha toxin. These data compare the response of alveolar macrophages to S. aureus with or without alpha toxin neutralization. Overall design: We used microarrays to detail the response of alveolar macrophages to S. aureus with or without alpha toxin neutralization.