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InfoHiC models for cancer Hi-C prediction
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2024-05-16
相关数据集
3D genomics across the tree of life reveals condensin II as a determinant of architecture type
We investigated genome folding across the eukaryotic tree of life. We find four general manifestations of genome organization at chromosome-scale that each emerge and disappear repeatedly over the cou
NIAID Data Ecosystem60
A three-dimensional map of the human genome at kilobase resolution reveals prinicples of chromatin looping
We use in situ Hi-C to probe the three-dimensional architecture of genomes, constructing haploid and diploid maps of nine cell types. The densest, in human lymphoblastoid cells, contains 4.9 billion c
DataCite Commons2020-10-10 更新50
Capture of TAD reorganization endows variant patterns of gene transcription (RNA-Seq)
TAD (Topologically Associating Domain) reorganization occurs commonly in cell nucleus and contributes to gene activation and inhibition through separation or fusion of adjacent TADs. However, identifi
NIAID Data Ecosystem30
3D genomics across the tree of life reveals condensin II as a determinant of architecture type
GAMinG script (python) and sequence file (.dat) to prepare files to run molecular dynamics in GROMACS (see ndb.rice.edu for more info regarding how to run the simulations). Two .hic maps and two sampl
NIAID Data Ecosystem50
A complex regulatory landscape involved in the development of external genitals [4C-seq]. A complex regulatory landscape involved in the development of external genitals [4C-seq]
In vertebrates, developmental genes are often controlled by large regulatory landscapes matching the dimensions of topologically associating domains (TADs). In various ontogenic contexts, the associat
NIAID Data Ecosystem30
