Data sheet index below 1.

In vitro and in vivo growth screen data, HCC827 cells, Source data for Fig 1. Mini-library CRISPRi screen in HCC827 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank and orthotopic) replicates are included. 2. In vitro and in vivo growth screen data, H1975 cells, Source data for Fig 1. Mini-library CRISPRi screen in H1975 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank and orthotopic) replicates are included. 3. Metastases Source data. Source data for Fig 1. 4. Time course. Source data for S1 Fig. 5. Tumor weight and volume, Source data for Fig 1. 6. Metabolomics C13-Glucose, Isotopologue Source data for Fig 3. 7. Metabolomics C13-Glutamine, Isotopologue Source data for Fig 3. 8. Metabolomics C13-Glucose, Fractional Contribution Source data for Fig 3. 9. Metabolomics C13-Glutamine, Fractional Contribution Source data for Fig 3. 10. RNA-Seq in vitro neg vs. in vitro sgc14orf2, Source data for Fig 2. 11. RNA-Seq in vitro neg vs. in vitro sgMALSU1, Source data for Fig 2. 12. RNA-Seq in vitro neg vs. in vitro sgTMEM261, Source data for Fig 2. 13. RNA-Seq in vivo neg vs. in vivo sgMALSU1, Source data for Fig 2D. 14. Pathway analysis of c14orf2, MALSU1, TMEM261 15. Bioluminescence data. Source data for Fig 4. Radiance readings and normalized values for replicates are listed here. (XLSX)