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ATAC-seq in WT, SAGA and ATAC mutant mouse embryonic stem cells

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https://www.ncbi.nlm.nih.gov/sra/SRP322144
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Assess chromatin accessibility in WT and mutant ES E14 strains using ATAC-seq. Mutant strains are depleted for subunits of the coactivator complexes SAGA (Supt7l KO) or ATAC (Yeats2, Zzz3) using constitutive knock-out (KO) or the auxin-inducible degron (AID) system. Overall design: ATAC-seq was performed on 100.000 cells in two replicates (on two different days) with two independent clones. Samples 1-6 = day 1, Samples 7-12 = day 2.
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2021-09-16
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