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X-ray crystal structure of wild type HIV-1 protease in complex with GRL-09510

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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X-ray crystal structure of wild type HIV-1 protease in complex with GRL-09510 Descriptor: (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, Protease Authors: Yedidi, R.S, Delino, N.S, Das, D, Kaufman, J.D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H. Deposit date: 2017-03-11 Release date: 2017-09-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.9 Å) Cite: GRL-09510, a Unique P2-Crown-Tetrahydrofuranylurethane -Containing HIV-1 Protease Inhibitor, Maintains Its Favorable Antiviral Activity against Highly-Drug-Resistant HIV-1 Variants in vitro. Sci Rep, 7, 2017
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2017-03-11
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