RNA sequencing of MCF7 cells after vinigrol 6 hours treatment

This study compares the gene expression level in four cancer cell lines before and after vinigrol treatment. The Lexogen QuantSeq 3'mRNA-seq library kit or Hieff NGS MaxUp II Dual-mode mRNA Library Prep Kit for Illumina MaxUp II was used to prepare the RNA-seq libraries in this study. We identified the dysregulated genes during this progress and explored the potential mechanism of vinigrol induced cell death in breast cancer cells. Overall design: MCF7-ADR, ,MDA-MB-231 and T47D cells treated with vinigrol (50 micromoles) for 6 hours compared with the DMSO group. Overall design: Examination of gene expression level change after vinigrol 6 hours treatment