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PTIR1 acts as a suppressor of immunoproteasome and promotes cancer immune resistance. PTIR1 acts as a suppressor of immunoproteasome and promotes cancer immune resistance

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA714384
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资源简介:
Cancer cells evade host immune surveillance by virtue of poor immunogenicity. We identify a novel oncogene that acts as a promotor of tumor immune resistance, designated as PTIR1. Tumor-intrinsic PTIR1 is induced by RNA splicing and highly correlated with poor outcome of patients with cancer. Overall design: Study of tumor infiltration lymphocytes in Mock or PTIR1 expressing CT26 tumors using 10x scRNA-seq technologies.
创建时间:
2021-03-14
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