Crystal structure of the androgen receptor ligand binding domain in complex with SARM S-22

Crystal structure of the androgen receptor ligand binding domain in complex with SARM S-22 Descriptor: (2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide, Androgen receptor Authors: Bohl, C.E, Duke, C.B, Jones, A, Dalton, J.T, Miller, D.D. Deposit date: 2011-04-19 Release date: 2011-05-04 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Unexpected binding orientation of bulky-B-ring anti-androgens and implications for future drug targets. J.Med.Chem., 54, 2011