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Translation dysregulation in cancer as a source for targetable antigens.

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE272996
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We used MULTI-seq (McGinnis, Patterson, et al., Nature Methods, 2019) to perform multiplexed single-cell RNA-sequencing analysis of cryopreserved primary melanoma tumor samples isolated from mice inoculated with TYW2 WT or KO tumors. Presented data represent CD45+ immune cells isolated from both tumor backgrounds at two timepoints (D18 and D21). MULTI-seq barcoded CD45+ mouse immune cells were isolated using FACS and analyzed using 3' scRNA-seq (10x Genomics)
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2024-12-06
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