ThDP-Mn2+ complex of R413A variant of EcMenD soaked with 2-ketoglutarate for 35 min
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ThDP-Mn2+ complex of R413A variant of EcMenD soaked with 2-ketoglutarate for 35 min Descriptor: (4~{R})-4-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3-ium-2-yl]-4-oxidanyl-butanoic acid, 1,2-ETHANEDIOL, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, ... Authors: Song, H.G, Dong, C, Chen, Y.Z, Sun, Y.R, Guo, Z.H. Deposit date: 2015-11-02 Release date: 2016-11-02 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Two active site arginines are critical determinants of substrate binding and catalysis in MenD, a thiamine-dependent enzyme in menaquinone biosynthesis. Biochem. J., 2018
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2015-11-02



