Hippocampal structure in control and stressed WT and maLPA1-null mice in NeuN-stained sections.
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Mean values ± SEM. MaLPA1-null mice showed reduced hippocampal volume in the oriens, pyramidal and radiatum layers in the CA1 and CA3 areas; no structural alterations were observed in the DG. Chronic stress reduced the volume of the pyramidal layer in both genotypes; however, reduced DG granular layer volume was observed only in the stressed NULL genotype, implying a reduction in the density and total number of NeuN+ neurons. Scale bars: 100 µm, 5 µm. Post-hoc LSD tests:(*p(#p
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2015-12-02



