Cryo-EM structure of TMEM63A-digitonin-cholesterol
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Cryo-EM structure of TMEM63A-digitonin-cholesterol Descriptor: CHOLESTEROL, Mechanosensitive cation channel TMEM63A Authors: Lin, Y, Zhou, Z, Han, Y, Cheng, D, Wang, H, Ju, L, Zhang, Y, Cox, D.C, Corry, B. Deposit date: 2025-09-26 Release date: 2026-02-11 Last modified: 2026-04-08 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: TMEM63 proteins act as mechanically activated cholesterol modulated lipid scramblases contributing to membrane mechano-resilience. Nat Commun, 17, 2026
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2025-09-26
