Aggregation kinetics of synthetic and recombinant Aβ (1–42) and Aβ (1–40).

1 T1/2 beyond experimental window of 22 hours were not assessed2 Rec. met-Aβ refers to the recombinant peptide (See methods for full description).3 IPP refers to peptide addition immediately post-purification without any pre-treatment preparation4 All samples were aggregated in aCSF per materials and methods except for those denoted as prepared in sodium-phosphate (NaP) buffer5 Sonication of Aβ (1–40) for 10 minutes in aCSF prior to addition to neuronal culture does not significantly change aggregation kinetics of the Aβ (1–40) monomer directly after purificationAggregation kinetics of synthetic and recombinant Aβ (1–42) and Aβ (1–40).