Analysis of immunohistochemical staining of RAGE and HMGB1 for TETs.

The percentage of epithelial tumor cells displaying staining for cytoplasmic or nuclear RAGE or HMGB1 is indicated. Cytoplasmic or nuclear staining intensity was scored as follows: score 0-3; 0, no staining; 1, weak; 2, moderate; 3, strong.
TETs thymic epithelial tumors, RAGE receptor for advanced glycation endproducts, HMGB1 high mobility group box1, WHO World Health Organization, Intens. Staining intensity, TC thymic carcinoma;
* mean[range]
aThe staining intensity of cytoplasmic RAGE in TC and WHO type B2 thymomas was significantly higher than in thymomas of WHO types A, AB, B1 and B3 (p<0.001).
bCytoplasmic staining intensity for HMGB1 was significantly higher in WHO type B thymomas and TC compared to WHO types A and AB (p<0.001).
cNuclear staining intensity for HMGB1 was significantly higher in WHO type A and AB thymomas compared to the other WHO types (p<0.001).
dmild-to-moderate