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structure of plasmepsin II from Plasmodium Falciparum complexed with inhibitor DR718A

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Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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structure of plasmepsin II from Plasmodium Falciparum complexed with inhibitor DR718A Descriptor: 2-amino-7-phenyl-3-{[(2R,5S)-5-phenyltetrahydrofuran-2-yl]methyl}quinazolin-4(3H)-one, Plasmepsin-2 Authors: Recacha, R, Leitans, J, Tars, K, Jaudzems, K. Deposit date: 2015-03-28 Release date: 2016-01-13 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.62 Å) Cite: Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV. J.Med.Chem., 59, 2016

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2015-03-28
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