Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative CK147

Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative CK147 Descriptor: 28S rRNA, 4-[[9-(cyclohexylmethyl)-3-methylidene-5-(4-methylphenyl)sulfonyl-1,5,9-triazacyclododec-1-yl]sulfonyl]-~{N},~{N}-dimethyl-aniline, 5.8S rRNA, ... Authors: Pauwels, E, Shewakramani, N.R, De Wijngaert, B, Vermeire, K, Das, K. Deposit date: 2022-09-26 Release date: 2023-02-22 Last modified: 2023-03-15 Method: ELECTRON MICROSCOPY (2.79 Å) Cite: Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative. Sci Adv, 9, 2023