Highly Regioselective Coupling Reactions of Allylic and Propargylic Alcohol Derivatives with γ,γ-Dialkoxyallylic Zirconium Species via Zr-to-Cu Transmetalation
收藏NIAID Data Ecosystem2026-03-06 收录
数据链接：
官方服务：
资源简介：
In the presence of CuCN, reaction of γ,γ-dialkoxyallylic zirconium species 4, generated in situ by treating triethyl orthoacrylate with zirconocene−butene complex, with allylic and propargylic phosphates proceeded at the α-position of 4 in a highly SN2‘-selective manner to give the corresponding 5-alkenoates and 4,5-alkadienoates, respectively. In the present Cu(I)-mediated coupling reaction, the γ,γ-dialkoxyallylic zirconium species 4 serves as a synthetically useful homoenolate anion equivalent of propionate.
创建时间：
2016-05-06
