Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-001
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Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-001 Descriptor: (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-methoxy-3-[4-[4-(1~{H}-1,2,3,4-tetrazol-5-yl)phenoxy]butoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... Authors: Singh, A.K, Brown, D.G. Deposit date: 2016-05-22 Release date: 2017-11-29 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity. J. Med. Chem., 61, 2018
创建时间：
2016-05-22
