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Copy number variation and expression of exportin-4 associates with severity of fibrosis in metabolic associated fatty liver disease

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP328169
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资源简介:
A duplication in the exportin 4 (XPO4) CNV reduces the expression of hepatic XPO4 leading to maintaining sustained activation of SMAD3/SMAD4 and liver fibrosis. Overall design: We overexpressed Xpo4 in JS-1 cells with and without treatment of TGFß and undertook RNA-Seq analysis and compared to empty vector control
创建时间:
2021-09-01
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