Evaluation of a chimeric YF-ZIK vaccine candidate in rhesus macaques

ChEBI2025-10-28 更新2026-07-12 收录

疫苗临床前评估

病毒疫苗开发

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-15887 数据链接链接失效反馈

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Evaluation of a chimeric YF-ZIK vaccine candidate in rhesus macaques

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2025-10-28

Activation of Innate and Adaptive Immunity by a Recombinant Human Cytomegalovirus Strain Expressing an NKG2D Ligand

病毒疫苗开发

免疫激活机制

Development of an effective vaccine against human cytomegalovirus (HCMV) is a need of utmost medical importance. Generally, it is believed that a live attenuated vaccine would best provide protective

NIAID Data Ecosystem90

Candidate Vaccine Assessment in a pH1N1 Rhesus Macaque Challenge Model

疫苗临床前评估

流感病毒防护

A mixed-aerosol pH1N1 (Cal04) challenge of rhesus macaques was establised to serve as a pre-clinical model for the evaluation of candidate vaccines. After characterizing the clinical signs and immune

NIAID Data Ecosystem40

A bivalent live-attenuated vaccine candidate elicits protective immunity against human adenovirus types 4 and 7

病毒疫苗开发

减毒活疫苗研究

Human adenovirus types 4 (HAdV4) and 7 (HAdV7) often lead to severe respiratory diseases and occur epidemically in children, adults, immune deficiency patients, and other groups, leading to mild or se

Figshare2021-12-13 更新30

Human Cytomegalovirus Vaccine Based on the Envelope gH/gL Pentamer Complex

病毒疫苗开发

抗体中和效力

Human Cytomegalovirus (HCMV) utilizes two different pathways for host cell entry. HCMV entry into fibroblasts requires glycoproteins gB and gH/gL, whereas HCMV entry into epithelial and endothelial ce

NIAID Data Ecosystem80

Zika virus strain PRVABC59 Sequencing

寨卡病毒基因组测序

病毒疫苗开发

Here, we sequenced a ZIKV stock, strain PRVABC59, used for inoculation. The virus was originally isolated from a traveler to Puerto Rico and underwent three passages on Vero cells and two rounds of am

NIAID Data Ecosystem40

Evaluation of a chimeric YF-ZIK vaccine candidate in rhesus macaques

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