BCL10 binds CARD9

B-cell lymphoma/leukemia 10 (BCL10) is the downstream signaling partner of CARD9 and it interacts selectively with the CARD activation domain of CARD9. BCL10 functions as an adaptor between the effector IKK complex and the proximal signaling complexes that interact with CARD9 (Bertin et al. 2000).

B细胞淋巴瘤/白血病10（BCL10）是CARD9下游信号传导的合作伙伴，并选择性地与CARD9的CARD激活结构域相互作用。BCL10作为效应器IKK复合体与近端信号复合体之间的适配器，这些信号复合体与CARD9相互作用（Bertin等，2000年）。