SNR-degraded 129Xe ventilation MRI for the comparison of quantification methods

Driven by the need to quantify these functional MR images robustly, multiple classifiers have been proposed to determine ventilation defect percentages as well as other ventilated clusters. However, these various methods have yet to be harmonized, which creates a barrier to deploying quantitative 129Xe MRI for multi-center studies. Here, we seek to help the pulmonary functional MRI community standardize its analysis methods that can be used going forward. To facilitate this endeavor we have made the images, as well as their SNR-degraded versions publicly available.