SntB triggers the antioxidant pathways to regulate development and aflatoxin biosynthesis in Aspergillus flavus

In this study, sntB gene deletion (?sntB), complementary (Com-sntB), and HA tag fused to snt2 strain (snt2-HA) strains were constructed by using the homologous recombination method, respectively. It was found in this study that SNTB plays a key role in development, secondary metabolism and pathogenicity of A. flavus. The mechanism was explored by Chromatin immunoprecipitation sequencing (ChIP-seq) and RNA sequencing (RNA-seq). Overall design: To reveal the potential complex regulatory network of the sntB, RNA-seq analysis was carried out on the WT and ?sntB strains. ChIP-seq analysis was carried out on the WT and sntB-HA strains.