Univariate analyses of risk factors for a severe decline in the platelet count and severe thrombocytopenia during 3-day continuous veno-venous hemofiltration.

APACHE: acute physiology and chronic health Evaluation; OR = odds ratio; CI = confidence interval; CVVH: continuous veno-venous hemofiltration; RRT: renal replacement therapy; LMWHs: low molecular weight heparins; SOFA: sequential organ failure assessment.aDecreased volume refers to average positive fluid balance less than 0 ml/d (insensible water loss was not included in the calculations); Increased volume refers to average positive fluid balance more than 1500 ml/d; volume balance refers to fluid balance in between.