A core UPS molecular complement implicates unique endocytic compartments at the parasite-host interface in Giardia lamblia – native IP conditions

Affinity purification and mass spectrometry coupled to microscopy-based subcellular localization and signal correlation quantification techniques were employed to investigate protein complexes of eleven reported unconventionally-secreted putative and confirmed virulence factors of Giardia lamblia, all predicted to be cytosolic.