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PRMT5 genomic deregulation supports growth and stress tolerance in chronic lymphocytic leukemia

ChEBI2020-08-19 更新2026-07-12 收录

慢性淋巴细胞白血病

PRMT5基因调控

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-8203 数据链接链接失效反馈

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PRMT5 genomic deregulation supports growth and stress tolerance in chronic lymphocytic leukemia

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2020-08-19

慢性淋巴细胞白血病

表观遗传学

Table S1. Overlap and enrichment of repeated elements along dREs. Table S2. Enrichment of dREs in the regulatory domains of CLL-up/down-regulated genes. Table S3. Enrichment of gene groups to Gene Ont

DataCite Commons2024-12-16 更新100

Characterization of CD200 Ectodomain Shedding

CD200胞外域脱落

慢性淋巴细胞白血病

We have previously reported the existence of a soluble form of CD200 (sCD200) in human plasma, and found sCD200 to be elevated in the plasma of Chronic Lymphocytic Leukemia (CLL) patients. CLL cells r

NIAID Data Ecosystem70

Germline Allele-Specific Expression of DAPK1 in Chronic Lymphocytic Leukemia

慢性淋巴细胞白血病

等位基因特异性表达

We previously reported a rare germline variant (c.1-6531) that resulted in allele–specific expression (ASE) of death-associated protein kinase 1 (DAPK1) and predisposition to chronic lymphocytic leuke

Figshare2016-01-18 更新20

Analysis of DNA methylation in normal B cells and chronic lymphocytic leukemia

DNA甲基化

慢性淋巴细胞白血病

Charting differences between tumors and normal tissue is a mainstay of cancer research. However, clonal tumor expansion from complex normal tissue architectures potentially obscures cancer-specific ev

NIAID Data Ecosystem90

Clinical and biological implications of target occupancy in chronic lymphocytic leukemia treated with acalabrutinib

BTK抑制剂药物

慢性淋巴细胞白血病

Inhibition of the B-cell receptor pathway, and specifically of Bruton tyrosine kinase (BTK), is a leading therapeutic strategy in chronic lymphocytic leukemia (CLL). Target occupancy has been measured

NIAID Data Ecosystem30

PRMT5 genomic deregulation supports growth and stress tolerance in chronic lymphocytic leukemia

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