Gfi1 knockout in Raw264.7 macrophages

Gfi1 is a transcription factor broadly participate in differentiation of immune cells and loss of Gfi1 could result in severe neutrophil deficiency. To gain insight into the consequences of lack of Gfi1 on a genome-wide level, we conducted genome-wide transcriptome profiling in Wide-type (WT) and Gfi1–/– Raw264.7 macrophage cells using Affymetrix Mouse 3’ IVT microarrays 7 samples are analyzed. Sample1-3 are Wildtype Raw264.7 cells as control group.Sample1-3 are Gfi1 Knockout cells.