Inhibition or genetic deletion of poly(ADP-ribose) polymerase-1 (PARP-1) is profoundly protective against a number of toxic insults in many organ systems1,2. In the brain the molecular mechanisms unde
Source data for Casterton et al. 2026 Karyoptosis mediates cell death and neurodegeneration upon proteotoxic stress. Supplementary Figure 2 and Figure 3 - part 2