Additional file 9: of Geminin prevents DNA damage in vagal neural crest cells to ensure normal enteric neurogenesis

Figure S8. ENS progenitors established in the gut are resistant to γ-irradiation in the first 2 hours following exposure. Cryosections at the level of the foregut of Wnt1Cre|EYFP control E10.5 embryos (A, B) or Wnt1Cre|EYFP embryos 2 hours (C, D) or 5 hours (E, F) following exposure to irradiation, immunostained for GFP (green) and processed for TUNEL (red). (G), Quantification of GFP+ ENCCs that are undergoing apoptosis (TUNEL+). One-way ANOVA followed by Fisher’s LSD multiple comparison test, ****P value < 0.0001. Scale bar: (A–F) 100 μm. (XLSX 16 kb)